Es wurden 46 Produkte zu dem Suchbegriff Fungal infection in 11 Shops gefunden:
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Scholl Fungal Nail Kur gegen Nagelpilz 3.8 ml
Anbieter: Notino Preis: 16,32 € (+4,45 €)Scholl Fungal Nail, 3.8 ml, Nägel für Damen, Nur auf gut gepflegten und gesunden Nägeln kann Ihre Maniküre wirklich zur Geltung kommen. Das Produkt Scholl Fungal Nail gewährleistet eine professionelle Pflege Ihrer Nägel. Brüchige oder geschwächte Nägel, die zum Ausfransen neigen, werden gestärkt, matte und geschädigte Nägel erhalten einen gesunden Glanz. Dank der speziellen, pflegenden Formulierung bleiben die Nägel fest und elastisch, sodass sie in Länge und Schönheit wachsen können. Es wird von allen geschätzt, die ihren Nägeln ihre natürliche Schönheit und ihr gesundes Aussehen zurückgeben wollen. Eigenschaften: regeneriert wirksam die Fingernägel stärkt die Fingernägel unterstützt ein gesundes Wachstum der Fingernägel Anwendung: Eine Schicht direkt auf den Fingernagel auftragen.
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Atlas of Fungal Infection
Anbieter: Thalia.de Preis: 108,99 €The Atlas of Fungal Infection is a comprehensive guide to the panoply of infections caused by fungi, emphasizing the visual clues to diagnosis of specific fungal diseases. The coverage extends across the entire spectrum of fungal infection, highlighting every known disease from noninvasive cutaneous infections to systemic involvement with endemic mycoses, to disease from a wide variety of opportunistic pathogens. Features hundreds of high quality images, and in-depth explanations for each page.
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Infection Free Zone
Anbieter: Instant-gaming Preis: 28,86 €Infection Free Zone
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BINGOSPA Foot Balm for Fungal Infection Foot Fungus Cracks Between Toes 135g
Anbieter: Kaufland.de Preis: 3,53 € (+6,50 €)Bingospa Balsam zur Pflege von zu Mykosen neigenden Füßen 135 g Fußpilz ist eine Hautinfektion, die durch Pilze, hauptsächlich Dermatophyten, verursacht wird und die Haut befällt Plantarfläche der Füße, Finger und Interdigitalfalten . Fußpilz ist eine der häufigsten Formen einer Pilzinfektion. Bei einer kürzlich in unserem Land durchgeführten -Forschung wurde festgestellt, dass jede dritte Person, bei der eine Pilzinfektion der Haut und der Nägel diagnostiziert wurde, an Fußpilz leidet. Es ist nach Nagelpilz die zweithäufigste Form einer Pilzinfektion.Der Balsam zur Pflege von zu Mykosen neigenden Füßen enthält unter den Wirkstoffen : fünf aktive Extrakte: Schafgarbe, Zitronenmelisse, Thymian, Schöllkraut, Eichenrinde, Pfefferminzöl (Menthol), Zinkoxid, Bienenwachs, Vaseline, Paraffinöl.Anwendung: Massieren Sie den Balsam sanft in die Haut der Füße ein. Verwenden Sie 3-4 mal täglich für 5 Tage. Als vorbeugende Maßnahme einmal täglich. Nicht verwenden, wenn Sie gegen einen der Inhaltsstoffe des Balsams allergisch sind. Nicht auf offenen Wunden anwenden, Kontakt mit Schleimhäuten vermeiden.Gewicht 135g BingoSpa Balsam do stóp ze skonnociami do grzybicy, 135g
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Black Jack - Infection | Zustand: Neu & original versiegelt
Anbieter: Buyzoxs Preis: 49,99 € (+4,95 €)Black Jack - Infection
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Springer US Fungal Infection in the Intensive Care Unit
Anbieter: Link.springer.com Preis: 117,69 €Fungal infections are an increasing problem in critically ill patients and these infections carry an attributable mortality that is much higher than corresponding bacterial infections. In both Europe and North America, Candida infections predominate and much of this book concentrates on the epidemiology, risk factors, diagnosis, and treatment of these infections. Particular reference is made to the cross-infection problems of Candida infection and the importance of infection control and preventative measures. However, other fungal infections are increasingly being seen in critically ill patients. This book is designed to offer a European and North American perspective on each topic. There are many similarities in experience and clinical practice but also significant differences that we hope will stimulate further thought and study. We hope the book will be of interest to intensivists, infectious disease specialists, medical microbiologists, and all those with an involvement in critical care. Progress in intensive care medicine is resulting in a growing population of critically ill patients at risk of fungal infection. Further improvements in survival will require a multidisciplinary approach.
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The Vaping Flavour Coconut Infection Rework Longfill Aroma
Anbieter: Steam-Time Preis: 12,90 € (+0,39 €)The Vaping Flavour Coconut Infection Rework Longfill Aroma: Ein unwiderstehlicher GeschmacksinfektEntdecken Sie das The Vaping Flavour Coconut Infection Rework Longfill Aroma, das eine verführerische Kombination aus reifen Beeren, exotischer Kokosnuss und himmlischer Cremigkeit bietet. Dieses Aroma verspricht, Ihr Geschmackszentrum zu infizieren und Ihre Geschmacksknospen in eine wahre Geschmackstrance zu versetzen. Bereiten Sie sich darauf vor, von den süßen und charakteristischen Noten dieses exquisiten Dampferlebnisses verzaubert zu werden.Einzigartige Mischung aus Beeren und KokosnussThe Vaping Flavour Coconut Infection Rework Longfill Aroma kombiniert die süßen, reifen Noten von Beeren mit dem aromatisch-süßen Charakter der Kokosnuss. Diese fruchtige und exotische Kombination wird durch eine reichhaltige und verführerische Creme abgerundet, die alle Komponenten harmonisch miteinander verschmelzen lässt und ein einzigartiges Dampferlebnis schafft.Verführerische Cremigkeit in jedem ZugDas Erlebnis des The Vaping Flavour Coconut Infection Rework Longfill Aromas ist wie ein sinnliches Dessert, das man dampfen kann. Die cremige Basis trägt die intensiven Fruchtnoten und ergänzt sie perfekt, um ein vollmundiges und ausgewogenes Geschmackserlebnis zu bieten, das Sie von Anfang an in seinen Bann ziehen wird.Einfache Zubereitung für ein perfektes ErgebnisDas Longfill Aroma wird in einer 60ml Chubby Leer-Flasche mit 10ml Aromakonzentrat geliefert. Mischen Sie es einfach mit Ihrer bevorzugten Base oder fügen Sie NicShots hinzu, um die gewünschte Nic-Stärke zu erreichen. Diese flexible Handhabung ermöglicht es Ihnen, das Aroma nach Ihren persönlichen Vorlieben zu gestalten und zu genießen.Ein Dampferlebnis, das süchtig machtMit jedem Zug des The Vaping Flavour Coconut Infection Rework Longfill Aromas erleben Sie ein Geschmackserlebnis, das Sie nicht mehr loslassen wird. Die Kombination aus süßen Beeren, exotischer Kokosnuss und verführerischer Creme ist so gestaltet, dass sie Ihr Geschmackszentrum infiziert und Sie immer wieder nach mehr verlangen lässt.
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Springer US Fungal Infections and Immune Responses
Anbieter: Link.springer.com Preis: 213,99 €Biomedical scientists widely acknowledge that individuals' immune respon siveness is important in resistance to infections by microorganisms, including fungi. Because of the devastating acquired immunodeficiency syndrome (AIDS) epidemic, caused by the human immunodeficiency retrovirus, it is now accepted that suppressed immune responses, especially cellular immu nity, are important contributors to increased individual susceptibility to opportunistic infections-including infections caused by fungi which were at one time thought to be very lowly or nonpathogenic. Within the last few years, there has been an almost explosive increase in interest and studies concerning the nature and mechanisms of the immune response to fungal infections. Many immunologists who are not well versed in mycology have begun to study the nature and mechanisms of antifungal immunity using a wide variety of newer as well as more conventional immunologic technologies, both in vivo and in vitro. Up to the 1980s, however, there was little interest among basic immunologists concerning fungal immunity. This situation has changed dramatically in the past half decade, mainly because of AIDS.
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The Vaping Flavour Coconut Infection Rework NicSalt Liquid 10ml / 10mg
Anbieter: Steam-Time Preis: 7,90 € (+0,39 €)The Vaping Flavour Coconut Infection Rework NicSalt Liquid – Fruchtig-cremiger Genuss mit exotischem FlairDas The Vaping Flavour Coconut Infection Rework NicSalt Liquid ist ein aromatisches Meisterwerk, das direkt aus dem „streng geheimen Labor“ der Aromaspezialisten kommt. Diese „Infektion“ trifft nicht den Körper, sondern ausschließlich die Geschmacksknospen – und das auf eine verführerische Weise! Ein cremiger Mix aus süßen, reifen Beeren und exotischer Kokosnuss sorgt für ein intensives Dampferlebnis, das man immer wieder genießen möchte. Eingebettet in eine verführerische Creme, zaubert diese exotisch-fruchtige Kombination einen Hauch Paradies in jeden Zug und lädt zum Dauergenuss ein.Exotische Kokosnuss trifft auf süße Beeren – Ein Geschmack, der süchtig machtJeder Zug des Coconut Infection Rework NicSalt Liquids entfaltet die charakteristischen Noten süßer Beeren, begleitet vom einzigartigen Aroma der Kokosnuss. Dieses Duett wird durch eine sanfte, cremige Basis abgerundet, die das fruchtig-exotische Erlebnis perfekt macht. Die intensiven Fruchtaromen und die cremige Kokosnote entführen die Sinne in exotische Gefilde und machen dieses Liquid unwiderstehlich.Perfekte Nikotinsalz-Stärken für intensiven GenussErhältlich in den Nikotinsalz-Stärken 10mg und 20mg/ml, ist das Coconut Infection Rework NicSalt Liquid ideal für Nutzer, die eine sanfte Nikotinzufuhr bei einem intensiven Geschmackserlebnis suchen. Die NicSalt-Formel sorgt für einen milden Throat Hit und eignet sich besonders für Umsteiger, die den Genuss von Nikotinsalz-Liquids in Pod-Systemen schätzen.Ausgewogenes Mischverhältnis für vollmundigen GeschmackMit einem Mischverhältnis von 50% VG und 50% PG bietet das Coconut Infection Rework NicSalt Liquid eine perfekte Balance zwischen intensiver Geschmacksentfaltung und reichhaltiger Dampfproduktion. Dieses Gleichgewicht garantiert ein gleichmäßiges und vollmundiges Vape-Erlebnis bei jedem Zug.Entwickelt für Pod-SystemeDas Coconut Infection Rework NicSalt Liquid wurde speziell für den Einsatz in Pod-Systemen entwickelt. Die kompakte Größe und die einfache Handhabung machen es zu einer idealen Wahl für unterwegs und ermöglichen ein unkompliziertes und angenehmes Dampferlebnis.Hochwertige Inhaltsstoffe für Premium-QualitätDas The Vaping Flavour Coconut Infection Rework NicSalt Liquid wird aus erstklassigen Inhaltsstoffen hergestellt. Die sorgfältige Auswahl von Propylenglykol, pflanzlichem Glycerin und hochqualitativen Aromen sorgt für ein unvergleichliches Dampferlebnis, das die geschmacksintensiven Fruchtaromen und die cremige Kokosnote perfekt zur Geltung bringt.Einfache Handhabung und sichere VerpackungDie handliche 10ml PET-Flasche mit kindersicherem Verschluss und Tropfaufsatz macht das Handling besonders einfach und sicher. Die kompakte Größe erlaubt es, das Liquid überallhin mitzunehmen und jederzeit zu genießen.
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Springer Nature Switzerland Fungal Infections
Anbieter: Link.springer.com Preis: 213,99 €In the last few years research on fungal infections has progressed significantly. Not only have the basic aspects of infections been further investigated but also clinical knowledge has advanced. Also methods to diagnose infections have advanced and robust epidemiological data have been generated, along with new therapeutical approaches created and optimized. To understand and critically evaluate such advances, this new, contemporaneous and dedicated material was founded. It brings together the most relevant data and highlights information in professional, clear, and scientific language to be used by professionals in healthcare systems and researchers in both private and public institutions. Fungal Infections covers recent research and discusses clinically relevant data. This book provides a comprehensive source where the reader can find necessary information from the basic concepts to the clinic and analytical methods. Another important aspect of this workis that it presents current therapies applied to fungal infections and reviews the latest therapeutical innovations, including in the pharmaceutical formulation field. This volume also details recent discoveries from a broad range of subjects from molecular biology to analytics and epidemiology; explains the most recent developments, for example, in terms of diagnostic methods and innovative therapy. It was written by world-class scientists in the field from various countries around the world with the highest quality standards, edited and revised in a peer-review style;. It also includes areas related to infectious diseases like immunocompromised patients, transplants, and immunological aspects, and gives recent data related to Covid-19. This book should be a valuable reference work for students in advanced courses in the medical field as well as for researchers and professionals working in the medical, pharmaceutical, biological, and biotechnological fields.
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The Vaping Flavour Coconut Infection Rework NicSalt Liquid 10ml / 20mg
Anbieter: Steam-Time Preis: 7,90 € (+0,39 €)The Vaping Flavour Coconut Infection Rework NicSalt Liquid – Fruchtig-cremiger Genuss mit exotischem FlairDas The Vaping Flavour Coconut Infection Rework NicSalt Liquid ist ein aromatisches Meisterwerk, das direkt aus dem „streng geheimen Labor“ der Aromaspezialisten kommt. Diese „Infektion“ trifft nicht den Körper, sondern ausschließlich die Geschmacksknospen – und das auf eine verführerische Weise! Ein cremiger Mix aus süßen, reifen Beeren und exotischer Kokosnuss sorgt für ein intensives Dampferlebnis, das man immer wieder genießen möchte. Eingebettet in eine verführerische Creme, zaubert diese exotisch-fruchtige Kombination einen Hauch Paradies in jeden Zug und lädt zum Dauergenuss ein.Exotische Kokosnuss trifft auf süße Beeren – Ein Geschmack, der süchtig machtJeder Zug des Coconut Infection Rework NicSalt Liquids entfaltet die charakteristischen Noten süßer Beeren, begleitet vom einzigartigen Aroma der Kokosnuss. Dieses Duett wird durch eine sanfte, cremige Basis abgerundet, die das fruchtig-exotische Erlebnis perfekt macht. Die intensiven Fruchtaromen und die cremige Kokosnote entführen die Sinne in exotische Gefilde und machen dieses Liquid unwiderstehlich.Perfekte Nikotinsalz-Stärken für intensiven GenussErhältlich in den Nikotinsalz-Stärken 10mg und 20mg/ml, ist das Coconut Infection Rework NicSalt Liquid ideal für Nutzer, die eine sanfte Nikotinzufuhr bei einem intensiven Geschmackserlebnis suchen. Die NicSalt-Formel sorgt für einen milden Throat Hit und eignet sich besonders für Umsteiger, die den Genuss von Nikotinsalz-Liquids in Pod-Systemen schätzen.Ausgewogenes Mischverhältnis für vollmundigen GeschmackMit einem Mischverhältnis von 50% VG und 50% PG bietet das Coconut Infection Rework NicSalt Liquid eine perfekte Balance zwischen intensiver Geschmacksentfaltung und reichhaltiger Dampfproduktion. Dieses Gleichgewicht garantiert ein gleichmäßiges und vollmundiges Vape-Erlebnis bei jedem Zug.Entwickelt für Pod-SystemeDas Coconut Infection Rework NicSalt Liquid wurde speziell für den Einsatz in Pod-Systemen entwickelt. Die kompakte Größe und die einfache Handhabung machen es zu einer idealen Wahl für unterwegs und ermöglichen ein unkompliziertes und angenehmes Dampferlebnis.Hochwertige Inhaltsstoffe für Premium-QualitätDas The Vaping Flavour Coconut Infection Rework NicSalt Liquid wird aus erstklassigen Inhaltsstoffen hergestellt. Die sorgfältige Auswahl von Propylenglykol, pflanzlichem Glycerin und hochqualitativen Aromen sorgt für ein unvergleichliches Dampferlebnis, das die geschmacksintensiven Fruchtaromen und die cremige Kokosnote perfekt zur Geltung bringt.Einfache Handhabung und sichere VerpackungDie handliche 10ml PET-Flasche mit kindersicherem Verschluss und Tropfaufsatz macht das Handling besonders einfach und sicher. Die kompakte Größe erlaubt es, das Liquid überallhin mitzunehmen und jederzeit zu genießen.
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Springer New York Vaccines for Invasive Fungal Infections
Anbieter: Link.springer.com Preis: 171,19 €This detailed volume focuses on the development of mycosis vaccines via the most common etiological agents of mycoses, such as Aspergillus and Candida species, followed by Cryptococcus, dimorphic fungi, and members of Mucoraceae family of fungi. The book is sectioned into five parts that describe experimental approaches for vaccine candidate discovery, improved vaccine design and delivery, assessment of critical endpoints, analysis of mechanisms of mycosis vaccine protection, and key methods for clinical translation. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting known pitfalls. Practical and authoritative, Vaccines for Invasive Fungal Infections: Methods and Protocols provides a standard reference forvaccine researchers, including those who aspire to strengthen their knowledge or desire to acquire a particular technique.
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Springer Nature Switzerland Fungal Infections
Anbieter: Link.springer.com Preis: 171,19 €In the last few years research on fungal infections has progressed significantly. Not only have the basic aspects of infections been further investigated but also clinical knowledge has advanced. Also methods to diagnose infections have advanced and robust epidemiological data have been generated, along with new therapeutical approaches created and optimized. To understand and critically evaluate such advances, this new, contemporaneous and dedicated material was founded. It brings together the most relevant data and highlights information in professional, clear, and scientific language to be used by professionals in healthcare systems and researchers in both private and public institutions. Fungal Infections covers recent research and discusses clinically relevant data. This book provides a comprehensive source where the reader can find necessary information from the basic concepts to the clinic and analytical methods. Another important aspect of this workis that it presents current therapies applied to fungal infections and reviews the latest therapeutical innovations, including in the pharmaceutical formulation field. This volume also details recent discoveries from a broad range of subjects from molecular biology to analytics and epidemiology; explains the most recent developments, for example, in terms of diagnostic methods and innovative therapy. It was written by world-class scientists in the field from various countries around the world with the highest quality standards, edited and revised in a peer-review style;. It also includes areas related to infectious diseases like immunocompromised patients, transplants, and immunological aspects, and gives recent data related to Covid-19. This book should be a valuable reference work for students in advanced courses in the medical field as well as for researchers and professionals working in the medical, pharmaceutical, biological, and biotechnological fields.
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Springer New York Vaccines for Invasive Fungal Infections
Anbieter: Link.springer.com Preis: 171,19 €This detailed volume focuses on the development of mycosis vaccines via the most common etiological agents of mycoses, such as Aspergillus and Candida species, followed by Cryptococcus, dimorphic fungi, and members of Mucoraceae family of fungi. The book is sectioned into five parts that describe experimental approaches for vaccine candidate discovery, improved vaccine design and delivery, assessment of critical endpoints, analysis of mechanisms of mycosis vaccine protection, and key methods for clinical translation. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting known pitfalls. Practical and authoritative, Vaccines for Invasive Fungal Infections: Methods and Protocols provides a standard reference forvaccine researchers, including those who aspire to strengthen their knowledge or desire to acquire a particular technique.
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Springer New York Vaccines for Invasive Fungal Infections
Anbieter: Link.springer.com Preis: 128,39 €This detailed volume focuses on the development of mycosis vaccines via the most common etiological agents of mycoses, such as Aspergillus and Candida species, followed by Cryptococcus, dimorphic fungi, and members of Mucoraceae family of fungi. The book is sectioned into five parts that describe experimental approaches for vaccine candidate discovery, improved vaccine design and delivery, assessment of critical endpoints, analysis of mechanisms of mycosis vaccine protection, and key methods for clinical translation. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting known pitfalls. Practical and authoritative, Vaccines for Invasive Fungal Infections: Methods and Protocols provides a standard reference forvaccine researchers, including those who aspire to strengthen their knowledge or desire to acquire a particular technique.
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Springer Netherlands Immunology of Fungal Infections
Anbieter: Link.springer.com Preis: 246,09 €The history of mankind has been shaped by infections, more than by war and famine together. At the same time, however, the development of society has had an equally important effect on human diseases. The emergence of agriculture, urban societies and high population densities has been proven to be crucial for the spread of pathogens, and thus human action is currently the single most important driver of infectious epidemiology. Even today, where once major killers such as poliomyelitis have been eradicated, new pathogens are appearing as result of human activity. One such group of pathogens are the fungi, whose emergence is mainly due to modern medical practices. Fungal microorganisms, from yeasts colonizing the skin or mucosa, to molds from soil or water, are usually harmless in the context of normal host responses. However, the success of chemotherapy, as well as the AIDS pandemia, has led to immune deficiencies in a significant segment of the patient population, and the extensive use of intravenous catheters has provided a way of access for microorganisms which otherwise would find difficult to infect the host. As a result, a yeast such as Candida is now on the 4th place on the list of the most frequent sepsis agents, whereas infection with the mold Aspergillus is increasing in incidence and it is one of the most feared complications in patients with hematological malignancies.
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Springer Netherlands Immunology of Fungal Infections
Anbieter: Link.springer.com Preis: 192,59 €The history of mankind has been shaped by infections, more than by war and famine together. At the same time, however, the development of society has had an equally important effect on human diseases. The emergence of agriculture, urban societies and high population densities has been proven to be crucial for the spread of pathogens, and thus human action is currently the single most important driver of infectious epidemiology. Even today, where once major killers such as poliomyelitis have been eradicated, new pathogens are appearing as result of human activity. One such group of pathogens are the fungi, whose emergence is mainly due to modern medical practices. Fungal microorganisms, from yeasts colonizing the skin or mucosa, to molds from soil or water, are usually harmless in the context of normal host responses. However, the success of chemotherapy, as well as the AIDS pandemia, has led to immune deficiencies in a significant segment of the patient population, and the extensive use of intravenous catheters has provided a way of access for microorganisms which otherwise would find difficult to infect the host. As a result, a yeast such as Candida is now on the 4th place on the list of the most frequent sepsis agents, whereas infection with the mold Aspergillus is increasing in incidence and it is one of the most feared complications in patients with hematological malignancies.
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Springer Netherlands Immunology of Fungal Infections
Anbieter: Link.springer.com Preis: 246,09 €The history of mankind has been shaped by infections, more than by war and famine together. At the same time, however, the development of society has had an equally important effect on human diseases. The emergence of agriculture, urban societies and high population densities has been proven to be crucial for the spread of pathogens, and thus human action is currently the single most important driver of infectious epidemiology. Even today, where once major killers such as poliomyelitis have been eradicated, new pathogens are appearing as result of human activity. One such group of pathogens are the fungi, whose emergence is mainly due to modern medical practices. Fungal microorganisms, from yeasts colonizing the skin or mucosa, to molds from soil or water, are usually harmless in the context of normal host responses. However, the success of chemotherapy, as well as the AIDS pandemia, has led to immune deficiencies in a significant segment of the patient population, and the extensive use of intravenous catheters has provided a way of access for microorganisms which otherwise would find difficult to infect the host. As a result, a yeast such as Candida is now on the 4th place on the list of the most frequent sepsis agents, whereas infection with the mold Aspergillus is increasing in incidence and it is one of the most feared complications in patients with hematological malignancies.
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Springer Berlin Heidelberg Combating Fungal Infections
Anbieter: Link.springer.com Preis: 213,99 €Fungi are eukaryotic microorganisms that are closely related to humans at cellular level. Human fungal pathogens belong to various classes of fungi, mainly zygo- cetes, ascomycetes, basidiomycetes, and deuteromycetes. In recent years, fungal infections have dramatically increased as a result of improved diagnosis, high frequency of catheterization, instrumentation, etc. However, the main cause remains the increasing number of immunosuppressed patients, mostly because of HIV infection and indiscriminate usage of antineoplastic and immunosuppressive agents, broad-spectrum antibiotics and prosthetic devices, and grafts in clinical settings. Presently available means of combating fungal infections are still weak and clumsy compared to control of bacterial infection. The present scenario of antifungal therapy is still based on two classes of antifungal drugs (polyenes and azoles). These drugs are effective in many cases, but display toxicity and limited spectrum of ef?cacy. The recent trend towards emergence of drug-resistant isolates in the clinic is an additional problem. In recent years, a few new antifungal drugs have entered the clinics, but they are expected to undergo same fate as the older antifungal drugs. The application of fungal genomics offers an unparalleled opportunity to develop novel antifungal drugs. However, it is too early to expect any novel drugs, as the antifungal drug discovery program is in the stage of infancy. Interestingly, several novel antifungal drug targets have been identi?ed and validated.
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Springer Berlin Heidelberg Combating Fungal Infections
Anbieter: Link.springer.com Preis: 213,99 €Fungi are eukaryotic microorganisms that are closely related to humans at cellular level. Human fungal pathogens belong to various classes of fungi, mainly zygo- cetes, ascomycetes, basidiomycetes, and deuteromycetes. In recent years, fungal infections have dramatically increased as a result of improved diagnosis, high frequency of catheterization, instrumentation, etc. However, the main cause remains the increasing number of immunosuppressed patients, mostly because of HIV infection and indiscriminate usage of antineoplastic and immunosuppressive agents, broad-spectrum antibiotics and prosthetic devices, and grafts in clinical settings. Presently available means of combating fungal infections are still weak and clumsy compared to control of bacterial infection. The present scenario of antifungal therapy is still based on two classes of antifungal drugs (polyenes and azoles). These drugs are effective in many cases, but display toxicity and limited spectrum of ef?cacy. The recent trend towards emergence of drug-resistant isolates in the clinic is an additional problem. In recent years, a few new antifungal drugs have entered the clinics, but they are expected to undergo same fate as the older antifungal drugs. The application of fungal genomics offers an unparalleled opportunity to develop novel antifungal drugs. However, it is too early to expect any novel drugs, as the antifungal drug discovery program is in the stage of infancy. Interestingly, several novel antifungal drug targets have been identi?ed and validated.
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