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Foodborne viruses are an important group of pathogens recognizedto cause significant disease globally in terms of both number ofillnesses and severity of disease. Contamination of foods by enteric viruses such ashuman norovirus and hepatitis A and E viruses is a major concern to publichealth and food safety. Food Virology is a burgeoning field of emphasis for scientificresearch. Many developments in foodborne virus detection prevention and control havebeen made in recent years and are the basis of this publication. This second edition of Viruses in Foods provides anup-to-date description of foodborne viruses of public health importance including theirepidemiology and methods for detection prevention and control. It uniquely includes casereports of past outbreaks with implications for better control of future outbreaks asection that can be considered a handbook for foodborne virus detection and updated andexpanded information on virus prevention and control with chapters on naturalvirucidal compounds in foods and risk assessment of foodborne viruses.

A compendium of readily reproducible and novel methods to manipulate DNA viruses and characterize their varied biological properties. The authors emphasize techniques for viral detection and genetics but also include methods for structure determination gene expression replication pathogenesis complex cellular models recombinant genetics and computational/systems approaches. Wide-ranging and highly practical DNA Viruses: Methods and Protocols will stimulate new directions in virology research with its novel strategies for engineering viral vectors in gene therapy and its advanced approaches for detecting viruses in human disease.

This book aims to provide a guide for virologists translational researchers and clinicians in the field of cancer research by providing reference protocols and methodologies from vector development through clinical translation. Written in the highly successful Methods in Molecular Biology series format chapters include introductions to their respective topics lists of the necessary materials and reagents step-by-step readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge Oncolytic Viruses: Methods and Protocols aims to ensure successful results in the further study of this vital field.

This book covers the entire spectrum of viral disease of the lung. It details the epidemiologic ultrastructural immunologic clinical and histop features of well-known viral pathogens as well as newer emergent infectious agents.

Hepatitis viruses research started more than fifty years ago. The names of hepatitis A and hepatitis B were introduced in 1947 when it became clear that there were two types of hepatitis that were transmitted either enterically or parenterally. It became apparent in the 1970's that there were additional hepatitis viruses distinct from hepatitis A and hepatitis B and thus the term non-A non-B hepatitis was introduced. The non-A non-B hepatitis was further divided into post-transfusion non-A non-B hepatitis and enterically-transmitted non-A non-B hepatitis in the 1980's. By the end of the 1980's both post-transfusion non-A non-B virus and enterically-transmitted non-A non-B virus had been identified and renamed hepatitis C virus and hepatitis E virus respectively. Hepatitis delta antigen was first recognized as an antigen associated with hepatitis B virus infection in the 1970's. In the early 1980's a virus was isolated and named hepatitis delta virus. These five different hepatitis viruses have distinct replication pathways and are major health concerns. They have become an important topic for teaching to graduate-level and medical students. Hepatitis Viruses provides a comprehensive up-to-date review of these viruses to readers. Each chapter is written by one of the top researchers in the field and topics include: the epidemiology and the natural history of infection of these viruses the molecular biology and the replication cycle of individual hepatitis viruses host-virus interactions and the pathogenesis of hepatitis viruses the immunology of hepatitis viruses the relationship between hepatitis viruses and hepatocellular carcinoma the viral vaccines and antiviral drugs. This book can serve as a supplemental reading material to graduate students and medical students and to any researcher who would like to learn more about hepatitis viruses.

Brand : University of Chicago Press, Binding : Taschenbuch, Edition : 3rd ed., Label : University of Chicago Press, Publisher : University of Chicago Press, Format : Illustriert, medium : Taschenbuch, numberOfPages : 159, publicationDate : 2021-03-29, releaseDate : 2021-03-29, authors : Carl Zimmer, ISBN : 022678259X

This is the first book entirely focused on viruses in foods. It collates information on the occurrence detection transmission and epidemiology of viruses in foods. This book also examines strategies for the prevention and control of viral contamination of food.

Foodborne viruses are an important group of pathogens recognizedto cause significant disease globally in terms of both number ofillnesses and severity of disease. Contamination of foods by enteric viruses such ashuman norovirus and hepatitis A and E viruses is a major concern to publichealth and food safety. Food Virology is a burgeoning field of emphasis for scientificresearch. Many developments in foodborne virus detection prevention and control havebeen made in recent years and are the basis of this publication. This second edition of Viruses in Foods provides anup-to-date description of foodborne viruses of public health importance including theirepidemiology and methods for detection prevention and control. It uniquely includes casereports of past outbreaks with implications for better control of future outbreaks asection that can be considered a handbook for foodborne virus detection and updated andexpanded information on virus prevention and control with chapters on naturalvirucidal compounds in foods and risk assessment of foodborne viruses.

A compendium of readily reproducible and novel methods to manipulate DNA viruses and characterize their varied biological properties. The authors emphasize techniques for viral detection and genetics but also include methods for structure determination gene expression replication pathogenesis complex cellular models recombinant genetics and computational/systems approaches. Wide-ranging and highly practical DNA Viruses: Methods and Protocols will stimulate new directions in virology research with its novel strategies for engineering viral vectors in gene therapy and its advanced approaches for detecting viruses in human disease.

DNA tumor viruses have long been useful experimental models of carcinogenesis and have elucidated several important mechanisms of cell transformation. Re search in recent years has shown that human tumors have a multifactorial nature and that some DNA tumor viruses may playa key role in their etiology. The aim of this book is to assess our knowledge of DNA tumor viruses by reviewing animal models mechanisms of transformation association with human tumors and possi bilities of prevention and control by vaccination. Animal models of tumor virology have contributed significantly to our under standing of the epidemiology and pathogenesis of virus-induced tumors. Bovine papillomaviruses induce papillomas in the intestine of cattle. The papillomas undergo a transition to carcinomas in cows feeding on bracken fern which pro duces a toxin with radiomimetic and immunosuppressive functions. This example of cooperation between a virus and chemical carcinogens parallels the cooperative role of human papillomaviruses (HPVs) and herpes simplex virus type 2 (HSV-2) with environmental carcinogens in the pathogenesis of cervical cancer. Likewise hepatocarcinomas appearing in woodchucks chronically infected by woodchuck hepatitis virus (WIN) provide strong support for the relationship between hepatitis B virus (HBV) infection and human hepatocellular carcinoma. Also the fact that WIN DNA integrates closely to cellular oncogenes suggests a possible molecular mechanism for the tumorigenesis induced by HBV.

This book describes the construction and purification of capsid-modified adenoviruses as well as oncolytic adenoviruses presents protocols for many virus species and describes the generation and testing of next-generation of oncolytic vaccinia virus.

This book focuses on the DNA viruses in the human population that are associated with cancers. It covers most of the viruses that are thought to contribute to human malignancy. The book represents a comprehensive review of the field of DNA tumor virology.

This volume offers a comprehensive review of tumor virology. It examines the many aspects of cancer-related viruses and how they contribute to cell proliferation the genes that are responsible for driving these cancers and their mechanisms of transmission.

This is the first book entirely focused on viruses in foods. It collates information on the occurrence detection transmission and epidemiology of viruses in foods. This book also examines strategies for the prevention and control of viral contamination of food.

This volume presents protocols that analyze and explore hemorrhagic fever viruses (HFV). This book is divided into 5 parts: Part I begins with an overview on predicting viral pandemics and then covers methods for surveillance diagnosis and classification of HFV. This includes an antibody capture method using Lassa virus antigens. Part II discusses structural studies and reverse genetics of HFV. The chapters in this part describe envelope glycoprotein membrane fusion studies arenavirus nucleocapsid protein and the use of virus-like-particles to study viral egress. Part III explores in vivo models of HFV infections and contains chapters on murine guinea pig and primate models for HFV and methods to obtain a subset of primary human liver cells that can be cultured long-term. Part IV looks into immune assays and vaccine production for HFV. The chapters in this section cover the attenuated vaccine for Argentine HFV detecting virus-antibody immune complexes in secondary dengue infections and DNA vaccination. Part V discusses host responses to viral hemorrhagic fever and contains chapters on identifying host restrictions to Junín or Dengue infection and a cell-culture method to assess coagulation after HFV infection. Written in the highly successful Methods in Molecular Biology series format chapters include introductions to their respective topics lists of the necessary materials and reagents step-by-step readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge Hemorrhagic Fever Viruses: Methods and Protocols is a valuable resource for scientists and researchers who want to bridge the gap between virus recognition in surveillance and understanding host responses to infection.

Brand : University of Chicago Press, Binding : Taschenbuch, Edition : 002, Label : UNIV OF CHICAGO PR, Publisher : UNIV OF CHICAGO PR, NumberOfItems : 1, PackageQuantity : 1, medium : Taschenbuch, numberOfPages : 128, publicationDate : 2015-10-09, authors : Carl Zimmer, ISBN : 022629420X

The expert contributors to this volume map new understanding of the influence of viruses on diabetes. They collate scattered research material and reexamine puzzles made amenable by new technologies such as the role of virus-induced cytokines.

Reoviruses are one of the most important viral groups for understanding the molecular and genetic basis for viral pathogenesis. These two volumes cover virtually all aspects of reovirus biology. Volume I begins with a review of reovirus structure; further chapters deal with functions of the reovirus structural proteins the assembly of the genome and reovirus mutants. Volume II reviews general mechanisms of reovirus persistent infection and cytopathic effects and then discusses reovirus-induced disease in specific organ systems including the heart nervous and endocrine systems liver and biliary system and intestine. Together these two volumes provide a current and comprehensive review of the mammalian reoviruses.

This detailed volume explores methods and techniques reflecting how viruses can be a beneficial force for all levels of life as well as the mammalian microbiota. Beginning with methods for the development and study of viruses the book continues with current techniques and approaches used to develop new treatments from virus-derived vaccines to vectors and proteins such as a range of models and methods designed to measure therapeutic efficacy of virus-derived biologics and therapeutic proteins. Written for the highly successful Methods in Molecular Biology series chapters include introductions to their respective topics lists of the necessary materials and reagents step-by-step readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical Viruses as Therapeutics: Methods and Protocols is an ideal guide for researchers working to further understand how viruses can benefit lifeforms and even prevent damage from other viruses.

There are over a million different species of insects and individually they 8 outnumber humans by more than 10 to 1. Moreover some insects live in close association with both plants and higher animals and naturally exchange viruses with them. It has even been speculated that viruses in general may have radiated through the plant and animal kingdoms from common insect origins. Be that as it may since insects play pivotal roles in the biosphere both to the benefit and detriment of mankind they and the viruses that infect them are important subjects for study. Insects are infected by a diverse medley of viruses and this volume focuses on those insect virus families that are found primarily or exclusively in insects. All major families of insect-selective viruses are covered except for the baculo viruses which were described in a separate volume of The Viruses series. Included in this volume are the established families of insect viruses the newly recognized ascovirus family and the nudiviruses which probably represent a separate family but currently remain unclassified. The coverage of arboviruses is limited to a single chapter that focuses on their potential utility as vectors and in insect control. Omitted for practical reasons are several individual insect viruses that have been described sporadically in the literature and probably represent novel virus families.